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X-WR-CALDESC:Events for CCMG | CCGM
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DTSTART;TZID=America/Toronto:20230331T120000
DTEND;TZID=America/Toronto:20230331T130000
DTSTAMP:20260626T152033
CREATED:20220902T210752Z
LAST-MODIFIED:20230329T153119Z
UID:10000013-1680264000-1680267600@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series March 2023
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nGenetic Test Interpretation from Pathogenicity to Variant Function\nDr. Las will present approaches to interpret clinical genetic tests of patients with neurodevelopmental disorders and epilepsy\, while considering variant pathogenicity and function.\nObjectives: \n\nIdentify the current status of genetics in neurodevelopmental disorders.\nAssess the use of genetic testing.\nConsider patient selection for precision medicine trials.\n\nSpeaker – Dr. Dennis Lal\nBio\nThe Lal Research Group focuses on the discovery\, evaluation\, and translation of biomarker into clinical care. Specifically\, we aim to develop computational methods which integrate large genetic\, clinical\, and biological data sets to improve the prediction of patient outcomes – paving the way for personalized medicine. \nDennis is Assistant Professor in the Department of Molecular Medicine in the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University (CCLCM) and Assistant Staff in the Genomic Medicine Institute with a secondary staff appointment in the Neurological Institute’s Epilepsy Center both Cleveland\, US. In addition to his primary appointments in Cleveland\, he is Visiting Scientist at the Broad Institute of Harvard and M.I.T.\, Cambridge\, US as well as Group Leader at the Cologne Center for Genomics\, Cologne\, Germany. \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-march-2023/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230224T120000
DTEND;TZID=America/Toronto:20230224T130000
DTSTAMP:20260626T152033
CREATED:20220902T210651Z
LAST-MODIFIED:20230221T220055Z
UID:10000012-1677240000-1677243600@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series February 2022
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nReconsidering Reproductive Carrier Screening\nA review of the tennets of reproductive carrier screening and points to provoke thought into what can be done better. A presentation of an update on advances of reproductive carrier screening. \nLearning Objectives \nConsider the rationale for carrier screening and different approaches\n– Compare the current practice in Canada vs elsewhere\n– Describe what has changed the landscape\n– Critique the pros and cons of panethnic and expanded carrier testing\n– Discuss where to go from her \nSpeakers bios \nDr. Joanna Lazier – Joanna Lazier is a Medical Geneticist at CHEO in Ottawa. She has a longstanding interest in prenatal and perinatal Genetics\, and founded the Prenatal Genetics Clinic in Edmonton. Upon moving to Ottawa in 2018\, she has become actively involved in prenatal and perinatal Genetics within the province of Ontario\, and is the chair of Prenatal Screening Ontario’s Genetics Working Group\, and the primary author of the CCMG position statement for the clinical application of fetal genome-wide sequencing during pregnancy. She is the chair of the CCMG Clinical Practice committee and co-chair of the CCMG Working Group on Reproductive Genetic Screening. \nDr. Ritu Aul – Dr. Aul is a Medical Geneticist who has been practicing in the GTA for more than 12 years. She completed her Medical Genetics residency at the University of British Columbia after medical school at Queen’s University. Dr. Aul has a special interest in prenatal screening and prenatal diagnosis. She currently sits on the CCMG Clinical Practice committee and co-chairs a working group with Dr. Lazier on updating current national guidelines for Reproductive Carrier Screening. \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-february-2022/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20230127T120000
DTEND;TZID=America/Toronto:20230127T130000
DTSTAMP:20260626T152033
CREATED:20220902T210601Z
LAST-MODIFIED:20230125T221946Z
UID:10000011-1674820800-1674824400@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series January 2023
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nJanuary 27\, 2023 – New Adventures in Neurogenetics \nDr. James Dowling\, Senior Scientist\, Program of Genetics and Genome Biology\nThe Hospital for Sick Children\nStaff Clinician\, Division of Neurology\, The Hospital for Sick Children\nProfessor\, Departments of Paediatrics and Molecular Genetics\, University of Toronto \n  \n  \n  \n  \n  \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-january-2023/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221216T123000
DTEND;TZID=America/Toronto:20221216T133000
DTSTAMP:20260626T152033
CREATED:20220902T211245Z
LAST-MODIFIED:20221206T204803Z
UID:10000017-1671193800-1671197400@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series December 2022
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nOverview of Diversity in Genomics Research and Medicine\nThis talk will provide an overview of diversity in genomics research and medicine\, including representation from different social and cultural groups. We will discuss the history and definitions of “race”\, “ethnicity”\, and “ancestry” as well as their current uses in genetics and genomic medicine. Audience members will reflect on their own work and deliberate best practices related to the use of population descriptors as categorical variables.\n\nLearning Objectives – by the end of this session\, attendees will be able to:\n\n\nIdentify conceptual issues related to the use of categorical population descriptors in genetics and genomic medicine.\nAssess current practices in clinical genetics research and medicine around the use of race\, ethnicity\, and ancestry.\nDecide on appropriate and inappropriate applications of population descriptors in future work.\n\n\nAlice Popejoy\, Epidemiology \n  \nSpeaker:\nDr. Alice Popejoy \nBio\nAlice Popejoy\, Ph.D. is an Assistant Professor in the Epidemiology Division of the Department of Public Health Sciences at the University of California\, Davis (UC Davis Health). She is also an Associate Member of the UC Davis Comprehensive Cancer Center. Dr. Popejoy’s research program in public health genetics is situated at the intersections of evolutionary genomics\, biomedical data science\, statistical genetics\, and the attending ethical\, legal\, and social implications (ELSI). She is currently focused on innovation and methods development to fundamentally shift the way human populations are categorized in biomedical research\, epidemiology\, and precision medicine. She received her B.A. from Hamilton College and her Ph.D. in public health genetics from the University of Washington. \n  \n  \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-december-2022/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221125T120000
DTEND;TZID=America/Toronto:20221125T130000
DTSTAMP:20260626T152033
CREATED:20220902T210407Z
LAST-MODIFIED:20221117T215238Z
UID:10000010-1669377600-1669381200@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series November 2022
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register. \n  \nTitle: Hereditary Cancer Surveillance Using Cell-Free DNA Sequencing \nCarriers of hereditary cancer syndromes are at heightened risk for malignancy and therefore undergo annual clinical screening for a host of cancers. As cancers are now well-known to shed cell-free DNA into the blood stream\, we founded the CHARM consortium (Cell-free DNA in Hereditary and High-risk Malignancies\, www.charmconsortium.ca) to assess whether regular genome and methylome profiling of blood plasma can detect the earliest cancers in this population. In this talk\, I will discuss findings from multiple different types of hereditary cancer syndromes utilizing a combination of mutational\, fragmentomic\, and epigenetic approaches to cell-free DNA analysis. I will also introduce data sharing and analytic strategies to increase the sensitivity and impact of these techniques. I will also provide an update on the current activities and future directions of the CHARM consortium. \nLearning objectives: \n\nUnderstand some of the challenges with the collection\, generation\, and interpretation of liquid biopsy data in clinical studies.\nDescribe different biological aspects of cell-free DNA and associated technologies to detect early cancer.\nIdentify opportunities in hereditary cancer to assess the use of cell-free DNA sequencing technologies for cancer screening.\n\n \nDr. Trevor Pugh PhD\, FACMG \nBio \nDr. Trevor Pugh\, PhD\, FACMG is a cancer genomics researcher\, board-certified molecular geneticist\, and holder of the Canada Research Chair in Translational Genomics. He is Director of the Joint Genomics Program of the University Health Network and Ontario Institute for Cancer Research which delivers basic\, translational\, and clinically-accredited genomics services. He is also appointed as Associate Professor in the\nUniversity of Toronto Department of Medical Biophysics\, Senior Scientist at the Princess Margaret Cancer Centre\, and Senior Investigator at the Ontario Institute for Cancer Research. His research lab is focused on understanding clinical implications of clonal shifts in cancer and non-cancerous cell populations during treatment\, most recently using cell-free DNA\, immune repertoire\, and single cell RNA-seq sequencing.\nMost recently\, he was recognized by Canada’s Top 40 Under 40\, the Canadian Cancer Society Bernard and Francine Dorval Prize\, a Terry Fox New Investigator Award\, and inclusion on the Web of Science Highly Cited Researchers List (top 1% of citations by field internationally).
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-november-2022/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20221028T120000
DTEND;TZID=America/Toronto:20221028T130000
DTSTAMP:20260626T152033
CREATED:20220902T210306Z
LAST-MODIFIED:20221019T213712Z
UID:10000009-1666958400-1666962000@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series October 2022
DESCRIPTION:This series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \n \nOctober 28 – RNA Sequencing In The Clinical Laboratory: The Sickkids Experience\nIn recent years\, the use of next-generation sequencing (NGS) and the ability to sequence the entire genome has increased the diagnostic rate for both rare diseases and cancer. However\, despite rapid advances in our understanding of the human genome\, nearly two-thirds of the patients with suspected rare genetic disorders remain without a conclusive molecular genetic diagnosis. RNA sequencing has the potential to improve our ability to interpret the functional and clinical significance of the genetic variants. We will review the role of RNA sequencing in a number of clinical scenarios and the path to developing and integrating innovative whole transcriptome analysis in clinical diagnostics. \nLearning objectives:\nDescribe the path to developing and implementing RNA sequencing in the clinical laboratory\nIdentify current and future clinical applications of RNA sequencing \nTarget audience: Geneticists\, Trainees\nCanMEDS Roles: Medical Expert (the integrating role)\, Collaborator\, Health Advocate\, Scholar\, Professional \n  \nBio\nDr. Lianna Kyriakopoulou is currently a director of Genome Diagnostics at the Hospital for Sick Children and Assistant Professor at the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She received her PhD in Microbiology and Molecular and Medical Genetics from the University of Toronto. She is certified by the Canadian Academy of Clinical Biochemistry and the American College of Medical Genetics in Clinical Molecular Genetics. Dr. Kyriakopoulou’s professional interests are in the areas of genetic metabolic disorders and diagnostic assay development using high-throughput methodologies and genomic tests\, particularly for rare disorders. \nAll Dates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-october-2022/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/Toronto:20220923T120000
DTEND;TZID=America/Toronto:20220923T130000
DTSTAMP:20260626T152033
CREATED:20220902T210107Z
LAST-MODIFIED:20220920T205745Z
UID:10000008-1663934400-1663938000@ccmg.51-222-78-205.ygkweb.ca
SUMMARY:Can-GARD/CCMG - The Leading Strand Series September 2022
DESCRIPTION:Seeking Equity For Precision Diagnosis Through The Silent Genome Project-governance\, Diagnostic And Bioinformatic Highlights With The Introduction Of Cafe (cohort Allele Frequency Estimation Pipeline). \nSummary:\nDrs Arbour and Wasserman will provide an overview of the progress of Silent Genomes Project to date including governance\, diagnostic and bioinformatic highlights on the path to build a sustainable Indigenous Background Variant Library. \nObjectives: \n\nIdentify on-going barriers to achieving equitable genetics/genomics care for Indigenous patients.\nDescribe challenges and potential solutions presented through the Silent Genome Project to provide equitable precision diagnosis for Indigenous patients.\nLearn about a protected\, sustainable solution to housing Indigenous specific genomic reference data in Canada.\n\nThis series is for genetics health professionals led by the Canadian College of Medical Genetics and co-sponsored by Can-GARD. Speakers will be translation-focused researchers\, clinicians and innovators.  The series will help attendees anticipate\, access\, and apply new approaches and technologies for patient care. \nDates \nSeptember 23\nOctober 28\nNovember 25\nDecember 16\nJanuary 27\nFebruary 24\nMarch 31\nApril 28\nMay 26\nJune 30 \nClick HERE to register. \nSpeaker bios \nDr. Laura Arbour is a Professor in the Department of Medical Genetics at the University of British Columbia\, situated at the Island Medical Program on Vancouver Island. Trained as both pediatrician and clinical geneticist (McGill University) her multifaceted Community Genetics Research Program addresses rare\, single gene disorders and complex conditions affecting Indigenous people. Her clinical practice encompasses rare genetic disease diagnosis and cardio-genetics. Her Northern BC work on Long QT syndrome led to the development of the BC Inherited Arrhythmia Program (BCIAP) for all British Columbians with inherited arrhythmias. She is also the project lead on a Genome Canada/Genome BC/CIHR funded Large Scale Applied Research Project\, entitled “Silent Genomes: Reducing health-care disparities and improving diagnostic success for Indigenous children with genetic disease” which aims to address the challenges of equitable access to genetic/genomic diagnosis and care for Canadian Indigenous populations. \n A professor in the Department of Medical Genetics at the University of British Columbia and based at BC Children’s Hospital\, Dr. Wyeth Wasserman’s computational biology research focuses on the analysis of the human genome. His laboratory conducts research in two overlapping domains: the control of gene activity and the identification of the causes of rare genetic disorders. His lab created the JASPAR database and a wide range of software which are used globally to identify the “on/off” switches in genes. Since low-cost DNA sequencing became accessible for patients\, his team works closely with clinicians at BC Children’s Hospital to discover the genetic causes impacting patients and families. He is a co-lead for the Silent Genomes Project and the lead for Activity 3\, the Development of an Indigenous Background Variant Library.
URL:https://ccmg.51-222-78-205.ygkweb.ca/event/can-gard-ccmg-the-leading-strand-series-september-2022/
CATEGORIES:Leading Strand
ORGANIZER;CN="CCMG | CCGM":MAILTO:info@ccmg-ccgm.org
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